HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Giovanna Zambruno Selected Research

Netherton Syndrome

5/2012A synonymous mutation in SPINK5 exon 11 causes Netherton syndrome by altering exonic splicing regulatory elements.
11/2011Proteolytic activation cascade of the Netherton syndrome-defective protein, LEKTI, in the epidermis: implications for skin homeostasis.
7/2006Corneodesmosomal cadherins are preferential targets of stratum corneum trypsin- and chymotrypsin-like hyperactivity in Netherton syndrome.
2/2006SPINK5, the defective gene in netherton syndrome, encodes multiple LEKTI isoforms derived from alternative pre-mRNA processing.
4/2005Characterization and expression analysis of the Spink5 gene, the mouse ortholog of the defective gene in Netherton syndrome.
1/2005Spink5-deficient mice mimic Netherton syndrome through degradation of desmoglein 1 by epidermal protease hyperactivity.
2/2002Netherton syndrome: disease expression and spectrum of SPINK5 mutations in 21 families.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown:


Giovanna Zambruno Research Topics

Disease

8Neoplasms (Cancer)
01/2021 - 01/2002
8Bullous Pemphigoid (Pemphigoid)
04/2012 - 01/2004
7Netherton Syndrome
05/2012 - 02/2002
7Melanoma (Melanoma, Malignant)
07/2008 - 01/2002
5Epidermolysis Bullosa Dystrophica (Dystrophic Epidermolysis Bullosa)
11/2021 - 12/2005
5Junctional Epidermolysis Bullosa (Epidermolysis Bullosa Letalis)
11/2021 - 09/2003
5Ichthyosis (Xeroderma)
10/2020 - 09/2014
5Pemphigus (Pemphigus Vulgaris)
01/2019 - 12/2008
4Wounds and Injuries (Trauma)
11/2015 - 10/2006
3Xeroderma Pigmentosum (Kaposi's Disease)
01/2021 - 09/2006
3Poikiloderma of Kindler
01/2013 - 01/2004
2Cardiomyopathies (Cardiomyopathy)
01/2022 - 11/2021
2Fibrosis (Cirrhosis)
05/2021 - 01/2019
2Trichothiodystrophy Syndromes
01/2021 - 02/2015
2X-Linked Ichthyosis (Ichthyosis, X Linked)
10/2019 - 07/2019
2Inflammation (Inflammations)
01/2019 - 01/2011
2Premature Aging
01/2019 - 04/2010
2Squamous Cell Carcinoma (Epidermoid Carcinoma)
11/2017 - 05/2014
2Cicatrix (Scar)
12/2015 - 02/2007
2Exfoliative Dermatitis (Erythroderma)
09/2015 - 02/2002
2Syndactyly (Polysyndactyly)
08/2014 - 08/2010
2Cleft Lip (Harelip)
08/2014 - 08/2010
2Ectodermal Dysplasia (Aplasia Cutis Congenita)
08/2014 - 08/2010
2Zlotogora-Ogur syndrome
08/2014 - 08/2010
2Epidermolysis Bullosa
05/2014 - 04/2010
2Hyperplasia
07/2012 - 06/2007
2Skin Diseases (Skin Disease)
01/2011 - 04/2007
2Autoimmune Diseases (Autoimmune Disease)
04/2010 - 12/2008
2Neoplasm Metastasis (Metastasis)
08/2006 - 08/2003
2Pathologic Neovascularization
08/2006 - 01/2006
1Epidermolysis Bullosa Simplex (Epidermolysis Bullosa Herpetiformis Dowling Meara)
01/2022
1Diarrhea
01/2022
1Reinfection
01/2022
1Ataxia (Dyssynergia)
11/2021
1Deafness (Deaf Mutism)
11/2021
1Palmoplantar Keratoderma (Keratosis Palmaris et Plantaris)
01/2021
1Erythema
01/2021
1Astrocytoma (Pilocytic Astrocytoma)
01/2021
1Nevus (Nevi)
10/2020
1Congenital Abnormalities (Deformity)
01/2019
1Blister (Bulla)
01/2019
1Cockayne Syndrome (Syndrome, Cockayne)
01/2019
1Foot Deformities (Foot Deformity)
01/2019
1Disease Progression
01/2019
1Genetic Skin Diseases
07/2017
1Immune System Diseases (Immune Disorders)
12/2015
1Vascular Diseases (Vascular Disease)
11/2015
1Ulcer
11/2015
1Papilloma (Papillomatosis)
08/2015

Drug/Important Bio-Agent (IBA)

13Proteins (Proteins, Gene)FDA Link
01/2022 - 01/2002
9AutoantibodiesIBA
01/2019 - 01/2004
7DNA (Deoxyribonucleic Acid)IBA
01/2021 - 09/2006
5Collagen Type VIIIBA
11/2021 - 12/2005
5Serine Proteinase Inhibitors (Serine Protease Inhibitors)IBA
10/2012 - 01/2005
4EpitopesIBA
11/2011 - 01/2004
4AntigensIBA
04/2010 - 02/2007
4Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
06/2007 - 01/2006
3Keratins (Keratin)IBA
01/2022 - 11/2004
3EnzymesIBA
10/2019 - 01/2007
3Placenta Growth FactorIBA
10/2006 - 01/2006
3Serine Peptidase Inhibitor Kazal-Type 5IBA
07/2006 - 02/2002
2UbiquitinIBA
01/2022 - 11/2021
2Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
11/2021 - 12/2015
2Protein Isoforms (Isoforms)IBA
11/2021 - 02/2006
2Laminin (Merosin)IBA
11/2021 - 11/2016
2Collodion (Nitrocellulose)IBA
01/2021 - 09/2015
2Nonsense Codon (Nonsense Mutation)IBA
07/2019 - 09/2011
2DesmogleinsIBA
01/2019 - 10/2012
2Keratin-14 (Keratin 14)IBA
12/2015 - 08/2006
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
11/2015 - 08/2003
2Messenger RNA (mRNA)IBA
11/2015 - 10/2006
2Streptozocin (Streptozotocin)FDA Link
11/2015 - 10/2006
2Cyclin-Dependent Kinase Inhibitor p16IBA
08/2015 - 04/2010
2Immunoglobulin E (IgE)IBA
01/2015 - 02/2002
2NectinsIBA
08/2014 - 08/2010
2IntegrinsIBA
09/2013 - 01/2013
2Peptide Hydrolases (Proteases)FDA Link
10/2012 - 01/2005
2CollagenIBA
04/2012 - 01/2002
2Vascular Endothelial Growth Factor CIBA
06/2007 - 08/2003
2Matrix Metalloproteinases (MMPs)IBA
02/2007 - 08/2006
2Temozolomide (Temodar)FDA LinkGeneric
10/2006 - 06/2004
2KalininIBA
10/2004 - 09/2003
1Ligases (Synthetase)IBA
01/2022
1Proteasome Endopeptidase Complex (Proteasome)IBA
01/2022
1Ophthalmic Solutions (Eye Drops)IBA
11/2021
1Extracellular Matrix ProteinsIBA
05/2021
1Staphylococcal Protein A (Protein A)IBA
01/2021
1Steryl-Sulfatase (Steroid Sulfatase)IBA
10/2019
1DecorinIBA
01/2019
1AntibodiesIBA
01/2019
1Surface Antigens (Surface Antigen)IBA
01/2019
1AutoantigensIBA
01/2019
1Transforming Growth Factors (Transforming Growth Factor)IBA
01/2019
1Reactive Oxygen Species (Oxygen Radicals)IBA
01/2019
1Keratin-6 (Keratin 6A)IBA
12/2015
1Interleukin-22 (IL-22)IBA
11/2015
1CytokinesIBA
11/2015
1EmollientsIBA
09/2015

Therapy/Procedure

4Therapeutics
11/2021 - 07/2012
1Parenteral Nutrition
01/2022